3 out of 5 liver cancers are preventable, new study discovers; cases could double in 25 years

Sixty percent of the 700,000 people who die each year from liver cancer could be prevented, reports a new study published in the journal Lancet.

That comprehensive research, according to a recent story by Nina Agrawal in The New York Times, finds that "prevention could be accomplished by addressing the disease's major causes: hepatitis B, hepatitis C, alcohol-associated liver disease, and liver disease linked to metabolic risk factors like obesity."

Dr. Brian P. Lee

The Times article quotes Dr. Brian P. Lee, an associate professor of medicine at the Keck School of Medicine at the University of Southern California, who was not involved in the study, to the effect that "liver cancer is common, it causes immense suffering and death, and the saddest part for me as a physician is that most of the cases are preventable."

Liver cancer is the sixth most common cancer and the third leading cause of death each year from cancer. There are nearly 900,000 new annual cases globally, Agrawal's piece indicates.

The story also quotes Dr. Ahmed Kaseb, a professor of gastrointestinal medical oncology at the University of University of Texas MD Anderson Cancer Center, who also wasn't associated with the study, as suggesting that the threat of liver cancer from heavy alcohol use and metabolic dysfunction-associated steatotic liver disease, or MASLD, formerly known as nonalcoholic fatty liver disease, "has been under-recognized and underestimated." 

Dr., Hashem El-Serag, chair of the department of medicine at Baylor College of Medicine in Texas and one of the authors of the new study, maintains that a vast majority of liver cancers arise in people with cirrhosis, advanced and largely irreversible scarring of the liver, which is definitively linked to heavy  alcohol consumption.

More information on the variety of cancers can be found in Rollercoaster: How a man can survive his partner's breast cancer, a VitalityPress book that I, Woody Weingarten aimed at male caregivers. My other books are MysteryDates — How to keep the sizzle in your relationship; The Roving I, a compilation of 70 of my newspaper columns; and Grampy and His Fairyzona Playmates, a whimsical fantasy intended for 6- to 10-year-olds that I co-authored with my then 8-year-old granddaughter. Check out my website at https://woodyweingarten.com for details.

EPA bans 2 cancer-causing chemicals used in everyday products — like dry-cleaning agents

While still under the aegis of Joe Biden,  the EPA banned two cancer-causing chemicals used in everyday products; now, many observers believe, it's only a matter of time until Donald Trump tries to revoke that decision.

The chemicals — perc, an industrial solvent used commonly in dry cleaning, and TCE, a substance found in consumer and manufacturing products (including de-greasing agents) — are known carcinogens, according to a recent story by Amudalat Ajasa in The Washington Post.

For instance, TCE, formally known as trichloroethylene, is associated with non-Hodgkin's lymphoma, leukemia, and kidney and liver cancers. The substance also is found in furniture care and auto repair products.

Perc, also known as PCE and perchloroethylene, is a solvent long used in applications of auto repair as well as in dry cleaning.

The two chemicals apparently have been seeping into the environment through the soil and waterways.

Michal Freedhoff, PhD

The Post article quotes Michal Freedhoff, the Environmental Protection Agency's assistant administrator for the Office of Chemical Safe and Pollution Protection and a PhD, to the effect that "the bans will protect workers, consumers, and residents from the chemical's harms."

Jonathan Kalmuss-Katz, a senior attorney at Earth Justice is also quoted: "Both of these chemicals have caused too much harm for too long, despite the existence of safer alternatives."

More information about carcinogens in the environment can be found in Rollercoaster: How a man can survive his partner's breast cancer, a VitalityPress book that I, Woody Weingarten, its author, aimed at male caregivers.

Medical risks expanding along with waistlines

Cancer dangers from obesity are growing exponentially, article in The Washington Post indicates

Obesity may overtake smoking as the No. 1 preventable cause of cancer.

According to a story by Laurie McKinley in The Washington Post a while back, the change is due to waistlines continuing "to expand while tobacco use plummets."

McKinley notes that Dr. Otis Brawley, ex-American Cancer Society (ACS) chief medical officer who's now a Johns Hopkins oncologist, says the switch may take five to 10 years.

Dr. Jennifer Ligibel

What's happening, she quotes Dr. Jennifer Ligibel, a breast oncologist at the Dana-Farber Cancer Institute, as saying, is that "a complex interplay of metabolism, inflammation and immunity…creates an environment that is more permissive for cancer."

The Post also quotes Dr. Jonathan Wright, a urologist at Fred Hutchinson Cancer Research, to the effect that "it does appear that the risk is greater the more obese you are."

Only about half the American public purportedly is aware of the link between excess weight and cancer. 

The deadly combo has long been known to increase the risk of heart disease and diabetes — and now is being associated, according to the Post, "with an increased risk of getting at least 13 types of cancer, including stomach, pancreatic, colorectal and liver malignancies, as well as postmenopausal breast cancer."

ACS researchers contend that "excess body weight is linked to about 8 percent of all cancers in the United States and about 7 percent of cancer deaths," McKinley reports.

She also writes that "compared with people of normal weight, obese patients are more likely to see their cancer come back and have a lower likelihood of survival. Perhaps more alarming, young people, who as a group are heavier than their parents, are developing weight-related malignancies, including colorectal cancer, at earlier ages than previous generations, experts say."

An article in JAMA Internal Medicine (the journal of the American Medical Association) several years ago maintained that "seven in 10 Americans are overweight or obese." But the obesity rate has been rising exponentially since that piece was published.

The type of cancer most associated with obesity, McKinley writes, "is endometrial, which develops in the lining of the uterus. Obese and overweight women are two to four times as likely to develop the disease as women of normal weight, and the risk rises with increased weight gain, according to the National Institutes of Health."

Statistics from that source also indicate that "people who are overweight or obese are twice as likely to develop liver and kidney cancer, and about 1.5 times as likely to develop pancreatic cancer than normal-weight people, according to NIH."

Several researchers, McKinley says, "are running clinical trials to prove what many already believe — that losing weight reduces the odds of developing cancer or having a recurrence." 

If studies show that to be true, she adds, "doctors could prescribe a weight-loss program as standard therapy for breast cancer patients — much as cardiac rehabilitation is urged for heart-attack patients. That could pave the way for insurance coverage."

More details on health risks can be found in "Rollercoaster: How a man can survive his partner's breast cancer," a VitalityPress book that I, Woody Weingarten, aimed at male caregivers.

5 cups of java might halve malignancy risks

Drinking coffee may help prevent some liver cancers, new British study suggests

A new British analysis shows that people who drink more coffee, even decaffeinated, are less apt to develop liver cancer.

The analysis took into consideration 26 studies, according to a story in a recent Guardian.

For those who drank two cups a day, the risk of hepatocellular cancer (HCC), the most common form of primary liver cancer, dropped by 35 percent compared to those who drank no coffee, the article reported.

"Those who drank one cup a day had a 20 percent lower risk," it added, noting, too, that for those who drank five cups, "the risk was halved." 

The research — published in the journal BMJ Open — was done by experts at the universities of Southampton and Edinburgh. It "examined data involving more than 2.25 million participants." 

Results also showed that "the protective effect for decaf was 'smaller and less certain than for caffeinated coffee.'"

The analysis' lead author, Dr. Oliver Kennedy of the U. of Southampton, was quoted as saying that coffee "is widely believed to possess a range of health benefits [but] we're not suggesting that everyone should start drinking five cups of coffee a day...There needs to be more investigation into the potential harms of high coffee-caffeine intake, and there is evidence it should be avoided in certain groups such as pregnant women."

According to another article — in the Southern Daily Echo, also a British publication — "liver cancer is one of the leading causes of cancer death globally because of its poor prognosis and high frequency…it is estimated that, by 2030, the number of new cases annually will have risen by about 50 percent to more than 1.2 million."

Cancer risks clearly come from a variety of sources, and reductions can come from multiple actions. Details can be found in "Rollercoaster: How a man can survive his partner's breast cancer," a VitalityPress book that I, Woody Weingarten, aimed at male caregivers.