Showing posts with label genetic testing. Show all posts
Showing posts with label genetic testing. Show all posts

Monday, May 17, 2021

Can you beat the odds of contracting disease?

Cancer prevention can be bettered by narrowing screenings, doing a Mediterranean diet, tracking genes


Smarter prevention is helping more Americans beat the odds of getting cancer.

That's the gist of a story by Marygrace Taylor in a Parade magazine some time ago — a story that's subdivided into categories that detail smarter screening, knowing your genes, eating Mediterranean, favorably using social media and eliminating from your lifestyle such an impediment to good health as tobacco.

Under the headline "The People vs. Cancer," the article notes that the overall cancer death rate is continuing to drop.

Referring to lung cancer, the piece contends there's growing evidence that "across-the-board testing might not be beneficial." Instead, it suggests, screening for those most at risk might be best.

Parade then quotes Dr. Peter Mazzone, Cleveland Clinic pulmonologist, to the effect that "the goal is to find ways — other than age and smoking history, to identify high-risk patients."

Mazzone had co-authored lung cancer screening guidelines with the American College of Chest Physicians for low-dose chest CT scans.

By specifically utilizing tests such as breath or blood tests that look for certain biomarkers, experts can minimize the harm done to patients (such as unnecessary biopsies), Taylor writes.

Genetic testing, on the other hand, can be enhanced by those who track their family's health history.

The story cites Dr. Charis Eng, director of the Center for Personalized Genetic Healthcare and chair of the Cleveland Clinic's Genomic Medicine Institute, who maintains that tracing a family tree should include determining who had what:

"The most important things are what's the diagnosis, age when diagnosed, family history and familial clustering of a disease."

It's also important to know, she told Parade, how a given disease presented itself. Such as "if a family member has been diagnosed with triple-negative breast cancer, we think there might be BRCA1 or BRCA2 [mutated gene] in the family."

Eating well, Taylor also indicates, can be a big preventive.

That may mean loading up "on whole grains, fruits and vegetables, nut and beans, olive oil and lean protein like fish." The writer, alluding to a Current Nutrition Reports review, notes that "a Mediterranean-style eating plan has been shown to protect against several types of cancer, including colon, prostate, stomach, esophageal, liver and endometrial cancers."

That diet in postmenopausal women, she adds, also was shown in a Dutch study to "slash the risk for certain breast cancers by up to 40 percent."

The story also quotes Jennifer McDaniel, a registered dietitian and co-author of Prevention Mediterranean Table, as saying that the cancer-fighting effect might also be due to what's not on the diet — foods like processed grains, white bread and rice, red meat and full-fat dairy products.

Why? McDaniel says that eating that way may support a healthy body weight and lower inflammation levels, which in turn help prevent some cancers.

Want to learn about other possible ways to avoid disease? Check out "Rollercoaster: How a man can survive his partner's breast cancer," a VitalityPress book that I, Woody Weingarten, aimed at male caregivers.

Friday, January 17, 2020

Actress pushes women's mental, physical health

Angelina Jolie promoting care for breast cancer patients, especially through loved ones, docs, research


More and more, Academy Award-winning actress Angelina Jolie is becoming known for her work outside Tinseltown.

Such as promoting caregiving for breast cancer patients — not only in regard to the care of loved ones but other aspects pertaining to "mental and emotional health, and physical safety."

Angelina Jolie
In a piece she wrote for a recent edition of Time magazine, Jolie, who's gained even more fame as a special envoy of the U.N. High Commissioner for Refugees, explains that "care is not just about medical treatments. It's also about the safety, dignity and support afforded to women, whether they're battling cancer or trying to manage other stressful situations."

Far too often, her column indicates, "they're not given nearly enough."

Jolie had a prophylactic double mastectomy in 2013 — plus surgery two years afterward to remove her ovaries and fallopian tubes — because she'd learned through a genetic test that she carried a mutation of the BRCA1 gene, which sharply increased her chances of developing breast and ovarian cancer.

The surgeries reduced but didn't eliminate those chances. With the operations, she writes, she had an estimated risk of 87 percent of getting breast cancer, 50 percent of ovarian.

Without the mutation, women typically have a 13 percent risk of breast cancer.

But Jolie, a contributing editor of Time, insists that without proper care, a female patient can fall apart not only because of risks of disease like cancer but "because of other pressures in her life that receive no attention at all…her family situation, her safety and whether she is carrying stress that is undermining her health and making her days much more difficult."

It should not take "someone getting sick to realize that faring for them and not harming them is necessary," she insists.

The now 44-year-old Jolie, who'd lost both mother and grandmother to breast cancer before their late 50s, adds that although there's been rapid progress in technology and science since her surgeries that can help "more people survive in the future and [be] able to live better lives during their illness," there's still "no reliable screening test for ovarian or prostate cancer…and no effective treatment for the most aggressive forms of breast cancer, known as triple negative cancers."

The actress, daughter of actor Jon Voight, while maintaining that care and support of loved ones is the most important factor in women's ability to cope with cancer and to face even the possibility of the disease, cites other related problems that plague modern females — post-traumatic stress disorder, for example, "anxiety, psychological distress, sexual violence and domestic violence."

And then, she writes, there's "poor mental health" stemming from "discrimination, overwork, poverty, malnutrition, low social status and unremitting responsibility for the care of others."

Care for patients is an integral part of "Rollercoaster: How a man can survive his partner's breast cancer," a VitalityPress book that I, Woody Weingarten, aimed at male caregivers.