Inaccurate DNA test plagued woman for more than a decade after double mastectomy

A Missouri woman's years of mental anguish stemmed from a DNA testing mistake.

According to Maureen Boesen's online story in the HuffPost, she "made major decisions — like having a double mastectomy — based on a false positive. I was robbed of the chance to breastfeed my babies, and it broke my heart."

The Kansas City mother of three's recent guest article contends she "just couldn't get past the fact that my inaccurate test result meant I had been carrying around a devastatingly unnecessary burden for more than a decade."

Because she and her two sisters have an extensive family history of cancer (ovarian and breast), Boesen not only opted for the preventive bilateral mastectomy at age 23 but was planning to have a complete hysterectomy by the age of 35. A second DNA test, with its negative result, quashed that idea — especially after a third test also showed she didn't have the dangerous BRAC1 gene mutation that would mean a 75% lifetime risk of getting breast cancer and a 50% chance of contracting ovarian cancer.

What was surprising, Boesen reported, was that the new results "were even more shocking and overwhelming than finding out I was positive. I was feeling so many emotions — confusion, sadness, anger, anxiety, depression, relief — all at once."

More information about false positives, BRCA1 and BRCA2 mutations, and other prophylactic surgeries can be found in ˆRollercoaster: How a man can survive his partner's breast cancer," a VitalityPress book that I, Woody Weingarten, aimed at male caregivers.

Brad Pitt comforts his wife 'throughout ordeal'

Angelina Jolie fighting early menopause after prophylactic surgeries to prevent cancer

Angelina Jolie and Brad Pitt

Actress Angelina Jolie, who recently had surgeries to ward off breast and ovarian cancer, is fighting early menopause as a result.

According to the Daily Dish, the 40-year-old told broadcaster Tom Brokaw that her 51-year-old husband, actor Brad Pitt, has comforted her "throughout the ordeal" and had made it clear "the surgeries wouldn't take anything away from the woman he fell in love with."

Jolie said he'd also indicated "that what he loved, and what was a woman to him, was somebody who was smart, and capable, and cared about her family. It's not about the physical body."

She knew throughout the surgeries, she elaborated, "that he was on my side and this wasn't something where I was gong to feel less of a woman — because my husband wasn't gonna let that happen."  

Jolie had her ovaries and Fallopian tubes removed in March, as a preventative measure, after doctors had found what might be early signs of ovarian cancer.

In 2013, the superstar had a prophylactic double mastectomy and reconstruction surgery after learning she carried the BRCA1 gene mutation that heightened her risk of developing breast cancer to about 87 percent. 

Her mom, Marcia Lynne "Marcheline" Bertrand, wife of actor Jon Voight, had died of ovarian cancer in 2007, at age 56, after an eight-year battle.

Rose Barlow, executive director of Zero Breast Cancer, a Marin County nonprofit dedicated "to prevention and finding the causes of breast cancer," has commented that "removing Fallopian tubes and ovaries not only significantly reduces the risk of those organs becoming diseased but also substantially reduces BRCA carriers' breast cancer rates."

Dish reported that Jolie told Brokaw in the joint interview on the "Today" show that "I knew the breast would be a bigger surgery and physically changing. The ovaries is more [about] your hormones changing and your emotions changing, but it's different — you feel different."

Pitt, praising his wife's lack of vanity, noted that the surgeries and aftermath together became "another one of those things in life that makes you tighter."

He added that "she was doing it for the kids, and she was doing it for her family, so [that] trumped everything and anything."

What's involved in being a male caregiver? "Rollercoaster: How a man can survive his partner's breast cancer" provides a detailed study of the role's ups and downs.

Celebrity backs testing for breast cancer gene

Kelly Osbourne lauds Angelina Jolie for airing her surgeries, promoting tests for mutation 

Kelly (left) and mom Sharon Osbourne

Reality TV star Kelly Osbourne apparently has the same gene mutation that superstar Angelina Jolie has.

So did Kelly's mom, Sharon.

But, unlike her mother, who had a double mastectomy in 2012, and Jolie, who opted to have both breasts removed two years ago and her ovaries and fallopian tubes just recently, Kelly's putting off any prophylactic surgery.

She did, however, praise Jolie (while being a guest on "The Talk") for going public about it all, according to the Daily Dish column on the SFgate.com website.

"I applaud Angelina," the site quoted her as saying, "because she's bringing attention to this and now people are going out and getting tested for it."

The BRCA1 gene, which all three have, puts them at a higher risk for breast and ovarian cancers.

In my new VitalityPress book, "Rollercoaster: How a man can survive his partner's breast cancer," I, Woody Weingarten, deal with many of the pros and cons regarding the gene and its risks — as well as the ups and downs of being a male caregiver.

If you click here, you can read the entire Daily Dish piece.